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. 2015 Aug 6;97(2):250–259. doi: 10.1016/j.ajhg.2015.06.005

Table 4.

Application of AVENGEME to Normally Distributed Traits Simulated on Real Genotypes

Pruned Clumped Independent
r2 0.1 0.2 0.1 0.2 0.1 0.2
Mean σˆ12 0.173 0.281 0.297 0.389 0.297 0.300
SD σˆ12 0.041 0.053 0.042 0.05 0.039 0.046
Mean πˆ01 0.559 0.579 0.900 0.879 0.949 0.931
SD πˆ01 0.428 0.400 0.066 0.080 0.02 0.096

Terms are as follows: pruned, markers are randomly retained in the reduced set; clumped, most strongly associated markers are greedily retained in the reduced set; r2, threshold on residual pairwise LD within the reduced set; independent, results for simulated markers with no LD between any pair. True σ12=0.3, π01 = 0.95.