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. 2015 Sep 17;15:84. doi: 10.1186/s12935-015-0233-x

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© Li et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Down-regulation of miR-125b reduced NSCLC metastasis. a NSCLC cells from different patients were transfected with miR-125b inhibitors for 12 h and then assayed for their expression of miR-125b. Each dot represented the results from one patient. b, c NSCLC cells from different patients were transfected with miR-125b inhibitors or the control, respectively, and then assayed for their adhesion activity (n = 4) and invasion (n = 5). d Nude mice were challenged LPS and NSCLC cells that were transfected with miR-125b inhibitors or the control. Lung tumor burden was detected by analyzing lung weight. Data were presented as means (±SD) from five nude mice in each group