Table 4.
Summary of findings of Preliminary Study | |||
---|---|---|---|
Allele | OR* (95%Cl) | p <0.1 | Comments |
HLA-A *30 | 7.2 | 0.089 | Most frequent in MS patient - marginally significant Amirzargar et al. (2005) Optical Neuritis; Bitti et al. (2001) |
HLA-A *02 | 0.7 | 0.552 | Smestad et al. (2007), Decreased risk of MS Bergamaschi et al. (2010); Protective allele |
HLA-DRB1 *01 | 11.0 | 0.041 | DeLuca et al. (2007) MS benign disease |
HLA-DRB1 *03 | 4.3 | 0.054 | Barcellos et al. (2006); Brynedal et al. (2007); Dean et al. (2007) Risk of MS |
HLA-DQB1 *04 | 0.23 | 0.066 | Marginally significant; Protective role; not described before |