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. Author manuscript; available in PMC: 2015 Sep 18.
Published in final edited form as: Bol Asoc Med P R. 2013;105(1):18–23.

Table 4.

Summarizes the most relevant findings of the HLA genotyping MS patients as a function of Odds Ratio (OR) and compare the numbers to the roles given by the researchers in other ethnic groups.

Summary of findings of Preliminary Study
Allele OR* (95%Cl) p <0.1 Comments
HLA-A *30 7.2 0.089 Most frequent in MS patient - marginally significant Amirzargar et al. (2005) Optical Neuritis; Bitti et al. (2001)
HLA-A *02 0.7 0.552 Smestad et al. (2007), Decreased risk of MS Bergamaschi et al. (2010); Protective allele
HLA-DRB1 *01 11.0 0.041 DeLuca et al. (2007) MS benign disease
HLA-DRB1 *03 4.3 0.054 Barcellos et al. (2006); Brynedal et al. (2007); Dean et al. (2007) Risk of MS
HLA-DQB1 *04 0.23 0.066 Marginally significant; Protective role; not described before