Table 4.
Dosimetric changes in OARs
| OARs | Parameter | Plan-0 | Plan-1 | Plan-2 | Plan-3 | Plan-4 | Plan-5 |
|---|---|---|---|---|---|---|---|
| BT | Dmax (Gy) | 53.21 ± 3.51 | 53.48 ± 4.59 | 53.51 ± 3.87 | 55.19 ± 3.40 | 55.84 ± 3.12 | 56.54 ± 3.72 |
| P value | 0.613 | 0.590 | <0.001 | <0.001 | <0.001 | ||
| SC | Dmax (Gy) | 40.74 ± 3.22 | 41.34 ± 3.36 | 43.08 ± 6.27 | 42.84 ± 5.72 | 42.66 ± 4.88 | 42.24 ± 3.87 |
| P value | 0.017 | 0.041 | 0.030 | 0.012 | 0.001 | ||
| PG-Lt | Dmean (Gy) | 34.31 ± 5.53 | 34.33 ± 5.58 | 35.23 ± 6.07 | 36.72 ± 6.67 | 37.17 ± 7.47 | 37.40 ± 7.62 |
| P value | 0.990 | 0.421 | 0.031 | 0.027 | 0.020 | ||
| V30 (%) | 47.08 ± 2.06 | 47.57 ± 2.95 | 50.35 ± 5.00 | 52.38 ± 3.93 | 51.33 ± 4.05 | 53.37 ± 4.72 | |
| P value | 0.773 | 0.229 | 0.017 | 0.063 | 0.010 | ||
| PG-Rt | Dmean (Gy) | 32.98 ± 3.58 | 33.31 ± 4.88 | 33.44 ± 4.61 | 34.69 ± 5.02 | 35.40 ± 3.93 | 38.58 ± 1.07 |
| P value | 0.673 | 0.533 | 0.083 | 0.003 | 0.038 | ||
| V30 (%) | 43.72 ± 6.49 | 44.79 ± 9.94 | 45.19 ± 9.16 | 48.34 ± 0.86 | 50.10 ± 8.51 | 51.61 ± 0.05 | |
| P value | 0.499 | 0.298 | 0.051 | 0.002 | 0.001 | ||
| Glottis | Dmean (Gy) | 40.97 ± 7.27 | 41.42 ± 7.67 | 41.51 ± 7.60 | 41.72 ± 7.46 | 41.45 ± 7.46 | 42.61 ± 9.69 |
| P value | 0.167 | 0.062 | 0.035 | 0.100 | 0.137 | ||
| Eye-Rt | Dmax (Gy) | 27.55 ± 8.34 | 30.30 ± 8.33 | 28.48 ± 8.30 | 30.20 ± 8.88 | 30.14 ± 9.45 | 29.79 ± 0.25 |
| P value | 0.057 | 0.321 | 0.014 | 0.016 | 0.090 | ||
| Lens-Lt | Dmax (Gy) | 6.87 ± 1.50 | 8.35 ± 3.40 | 8.04 ± 3.01 | 8.41 ± 3.27 | 8.56 ± 2.83 | 8.60 ± 3.91 |
| P value | 0.046 | 0.035 | 0.041 | 0.008 | 0.082 |
OARs organs at risk, BT brain stem, SC spinal cord, PG-Lt left parotid gland, PG-Rt right parotid gland, Eye-Rt right eye, Lens-Lt left lens