Table 4.
Effect of iron fortified complementary food | Effect of intermittent preventive treatment of malaria | |||
---|---|---|---|---|
Received CF-FeFuma | n = 250 | Received IPTa | n = 251 | |
No CF-FeFuma | n = 252 | IPT-placeboa | n = 251 | |
Odds ratiosb of anaemia (Hb concentration <11 g/dl) (95 % CI) | ||||
6 months | 0.64 | (0.33 to 1.25; P = 0.19) | 0.46 | (0.24 to 0.90; P = 0.023) |
9 months | 0.85 | (0.43 to 1.68; P = 0.64) | 0.46 | (0.23 to 0.90; P = 0.024) |
Odds ratiosc of iron deficiency (plasma ferritin concentration <30 µg/l) (95 % CI) | ||||
6 months | 0.28 | (0.14 to 0.56; P < 0.001) | 1.52 | (0.76 to 3.04; P = 0.23) |
9 months | 0.19 | (0.09 to 0.40; P < 0.001) | 1.64 | (0.79 to 3.42; P = 0.19) |
Odds ratiosb of malaria prevalence (P. falciparum) (95 % CI) | ||||
6 months | 1.17 | (0.68 to 2.01; P = 0.58) | 0.59 | (0.34 to 1.02; P = 0.057) |
9 months | 1.30 | (0.71 to 2.39; P = 0.39) | 0.61 | (0.33 to 1.12; P = 0.11) |
Odds ratiosb of the inflammation statusd (95 % CI) | ||||
6 months | 0.66 | (0.37 to 1.19; P = 0.17) | 0.52 | (0.29 to 0.94; P = 0.030) |
9 months | 0.82 | (0.44 to 1.51; P = 0.52) | 0.77 | (0.42 to 1.43; P = 0.41) |
aAssignment at baseline
bAdjusted for age
cAdjusted for age and CRP concentration
dInflammation is defined as CRP >5 mg/l and/or AGP >1 g/l
Odds ratios were assessed in 12- to 36-month-old Ivorian children at 6 and 9 months. The estimations are based on a 2 × 2 factorial analysis using a logistic regression model taking into account random effects