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Conservation of AcrB residues at mutant and suppressor sites
| AcrB homologa/bacterium | % amino acid homology to E. coli AcrB |
E. coli AcrB residue |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Y49 | V127 | D153 | G288 | F453 | L486 | F610 | F615 | ||
| AcrB/S. Typhimurium | 94.57 | Y | V | D | G | F | L | F | F |
| MexB/P. aeruginosa | 69.79 | Y | I | D | G | F | L | F | F |
| AcrD/E. coli | 65.77 | Y | V | D | G | F | M | F | S |
| MexD/P. aeruginosa | 47.93 | Y | L | T | G | F | L | F | F |
| CusA/E. coli | 20.45 | Y | L | D | G | F | I | F | K |
| DN30_1079/V. cholerae | 20.52 | Y | V | Y | N | F | I | T | K |
