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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Genes Brain Behav. 2015 Aug 25;14(7):526–533. doi: 10.1111/gbb.12235

Figure 3. AT1aR knockout from CRFergic cells has no effect on acquisition of conditioned fear, but leads to decreased fear expression and enhanced extinction retention.

Figure 3

(a) AT1aR(+/+) and CRF-AT1aR(−/−) mice show similar levels of freezing during fear acquisition (n=15–17). (b and c) During extinction, CRF-AT1aR(−/−) mice show significantly less freezing than AT1aR(+/+) mice overall and during the last 10 CS presentations (n=15–17).