TABLE 3.

Comparison of Mass Spectrometry and Immunoblotting Analyses

Protein Name	Mass Spectrometrya	IBb	Lectin IBb	Previously Associated With Sepsis
α-1-antichymotrypsin	↓ ↓	↔	↔
Antithrombin III	↑	↔	NE	(27)
Attractin	↑ ↓	↔	↔
Cathepsin L	↑	↓	NE
CD44	↔	↔	NE	(31)
CD276	↓ ↓ ↓	↔	NE	(30)
Cell adhesion molecule 1	↓	↔	NE
Clusterin	↔	↔	↓	(27)
Complement factor H	↑	↔	NE	(29)
Fc fragment of IgG binding protein	↓ ↓	↔	NE	(35)
Fibronectin	↓	↔	NE	(36)
Fibrinopeptide A	↔	↔	NE	(37)
Galectin-3	↔	↔	NE	(38)
Kininogen	↔	↑	NE	(21)
Leucine-rich glycoprotein 1	↑	↔	NE
Neutrophil gelatinase–associated lipocalin	↔	↓	NE	(21)
Periostin	↑	↓	NE
Tenascin-C	↓	↔	↔	(22)
Tissue factor protease inhibitor	↓	↔	NE	(39)
Vascular cell adhesion molecule	↓ ↓ ↓	↓	NE	(40)
Vascular endothelial growth factor C	↔	↔	NE	(41)
Vitronectin	↓	↔	NE	(42)

IB = immunoblotting, NE = not evaluated.

^aArrows indicate the number of peptides and the direction of change in nonsurvivors.

^bArrows indicate direction of change in nonsurvivors compared with survivors.

References for proteins previously associated with sepsis are included.