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. Author manuscript; available in PMC: 2015 Sep 18.
Published in final edited form as: Mol Biosyst. 2015 Sep 15;11(10):2770–2779. doi: 10.1039/c5mb00308c

Fig. 6.

Fig. 6

a) A general structure of a library of N-alkylated macrocyclic peptdies encoded by linear peptides. The macrocyclic peptide is 20-membered ring. b) Chemical structures of building blocks used at each position of the library. At peptoid position, bromoacetic acid (BAA) was used as acid submonomer while, at PTA position, R-BPA and S-BPA-d4 were used as acid submonomers. Note that (R) or (S) configuration at α-carbon of these units are inverted by amine displacement. Total diversity of the library is 98,304 compounds.