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. Author manuscript; available in PMC: 2016 Sep 14.
Published in final edited form as: Dev Cell. 2015 Aug 6;34(5):577–591. doi: 10.1016/j.devcel.2015.06.023

Figure 6. Genes from defined signaling pathways are highly expressed and specifically partitioned in embryonic skin.

Figure 6

(A) Genes involved in Wnt, Fgf, Bmp, Notch and Shh signaling were mined from the KEGG database and represented in the heat map if expressed (FPKM >1) in embryonic skin. Discussed genes are highlighted and color-coded for cell type. See also Figure S4.

(B) KEGG pathway analysis (Enrichr) for each cell type-specific molecular signature. Brighter tiles in the canvas indicate greater significance; notable terms are labeled. All terms and relevant genes are listed in Table S5.

(C) Signature (bolded) and other enriched genes related to axon guidance signaling are localized to specific cell types in embryonic skin. Connections indicate known interactions between two factors as mined from literature.