Table 4.
Changes of complete response rate, complete control rate, and total control rate after receiving olanzapine combined with standard antiemetic therapy.
| Acute phase (0–24 h) | Delayed phase (24–120 h) | Overall phase (0–120 h) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Without OLN | With OLN | P value* | Without OLN | With OLN | P value* | Without OLN | With OLN | P value* | |
| No vomiting | 44 (88%) | 50 (100%) | 0.03 | 35 (70%) | 48 (96%) | <0.001 | 31 (62%) | 48 (96%) | <0.001 |
| No rescue therapy | 27 (54%) | 49 (98%) | <0.001 | 1 (2%) | 41 (82%) | <0.001 | 1 (2%) | 41 (82%) | <0.001 |
| CR | 26 (52%) | 49 (98%) | <0.001 | 1 (2%) | 41 (82%) | <0.001 | 1 (2%) | 41 (82%) | <0.001 |
| CC | 24 (48%) | 49 (98%) | <0.001 | 0 (0%) | 41 (82%) | <0.001 | 0 (0%) | 41 (82%) | <0.001 |
| TC | 17 (34%) | 43 (86%) | <0.001 | 0 (0%) | 21 (42%) | <0.001 | 0 (0%) | 20 (40%) | <0.001 |
*McNemar test.
OLN: olanzapine.
CR: complete response (no vomiting, no rescue, and any nausea).
CC: complete control (no vomiting, no rescue, and nausea grade 0 or 1).
TC: total control (no vomiting, no rescue, and nausea grade 0).