Table 4.
Univariable and multivariable Cox regression models to predict RFS in 218 patients treated with nephrectomy with curative intent for pRCC.
| Variables | Univariable | P value | Stepwise analyses | P value |
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | |||
| Age greater than 60 | 0.74 (0.31–1.79) | 0.507 | ||
| Gender (male versus female) | 0.92 (0.34–2.54) | 0.875 | ||
| Symptoms at presentation (yes versus no) | 2.07 (0.79–5.41) | 0.138 | ||
| Hypertension (yes versus no) | 1.40 (0.56–3.46) | 0.471 | ||
| Diabetes mellitus (yes versus no) | 0.43 (0.06–3.24) | 0.414 | ||
| pTNM stage | ||||
| T (III versus II versus I) | 2.43 (1.50–3.92) | <0.001 | ||
| N1 versus pNx/0 | 5.82 (1.29–26.28) | 0.022 | ||
| TNM group (III versus II versus I) | 2.62 (1.62–4.26) | <0.001 | 2.19 (1.31–3.64) | 0.003 |
| Grade (G3-4 versus G1-2) | 3.24 (1.31–7.99) | 0.011 | — | — |
| pRCC type (type 2 versus 1) | 3.07 (1.21–7.77) | 0.018 | — | — |
| Tumor necrosis (yes versus no) | 3.10 (1.23–7.80) | 0.016 | 2.55 (0.97–6.70) | 0.057 |
| ANC (≥5.3/nL versus <5.3/nL) | 8.64 (2.39–31.15) | 0.001 | 4.71 (1.04–21.35) | 0.045 |
| ALC (≥1.3/nL versus <1.3/nL) | 0.43 (0.16–1.14) | 0.089 | ||
| NLR (≥3.6 versus <3.6) | 5.27 (2.11–13.17) | <0.001 | 4.01 (1.26–12.73) | 0.018 |