Table 2.
A comparison of patient characteristics and radiation pneumonitis in lung cancer patients treated with tomotherapy according to the delivery mode of radiation beams
| Mode of tomotherapy | P-value | |||
|---|---|---|---|---|
| Static | Helical | |||
| Smoking History | Yes | 12/12 (83.3 %) | 26/51 (51.0 %) | 0.04 |
| No | 2/12 (16.7 %) | 25/51 (49.0 %) | ||
| PTV (cc) | Median (range) | 158.50 (57–799) | 144.00 (16–789) | NS |
| Total lung V10 (%) | median (range) | 32.00 (11–70) | 44.00 (5–98) | NS |
| Total lung V20 (%) | median (range) | 16.00 (5–51) | 16.00 (4–53) | NS |
| CCRTx | Yes | 7/12 (58.3 %) | 14/51 (27.5 %) | 0.04 |
| No | 5/12 (41.7 %) | 37/51 (72.5 %) | ||
| Radiation pneumonitis scoring system | ||||
| RTOG | Acute | 3/ 12 (25.0 %) | 15/51 (29.4 %) | NS |
| Late | 1/ 12 (8.3 %) | 27/42 (64.3 %) | 0.001 | |
| CTCAE | Acute | 3/ 12 (25.0 %) | 20/51 (39.2 %) | NS |
| Late | 1/ 12 (8.3 %) | 20/42 (47.6 %) | 0.01 | |
CCRTx concurrent chemoradiotherapy, RTOG Radiation Therapy Oncology Group, CTCAE the National Cancer Institute Common Terminology Criteria for Adverse Events, version 3.0, NS not significant