Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Top 5 canonical pathways in pediatric endotype A vs. endotype B
| Pathway name | Number of genes |
|---|---|
| Nrf2-mediated oxidative stress response | 20 |
| Xenobiotic metabolism signaling | 17 |
| Aryl hydrocarbon receptor signaling | 13 |
| Superoxide radicals degradation | 5 |
| LPS/IL-1 mediated inhibition of RXR function | 12 |
Abbreviations: IL interleukin, LPS lipopolysaccharide, Nrf2 nuclear erythroid-related factor 2 p45-related factor 2, RXR retinoic acid receptor
