Table 3.
Distribution of the tag SNPs of KCNB1in case–control study
| SNP ID | IR(n = 199) | Non-IR(n = 534) | χ 2 | P 1 | P 2 | OR (95 % CI) |
|---|---|---|---|---|---|---|
| rs926672 | 6.76 | 0.03 | ||||
| AA | 60 | 182 | ||||
| AT | 109 | 246 | ||||
| TT | 24 | 100 | ||||
| AA vs TT | 0.25 | 1.37(0.80-2.35) | ||||
| AT vs TT | 0.03 | 1.77(1.07-2.93) | ||||
| AA vs AT | 0.18 | 1.29(0.89-1.88) | ||||
| Dominent model | 0.40 | 0.50 | 1.13(0.79-1.62) | |||
| Recessive model | 0.04 | 0.06 | 1.60(0.99-2.60) | |||
| rs2057077 | 6.33 | 0.04 | ||||
| CC | 62 | 200 | ||||
| TC | 111 | 252 | ||||
| TT | 20 | 80 | ||||
| CC vs TT | 0.44 | 0.89(0.67-1.19) | ||||
| CC vs TC | 0.11 | 1.35(0.94-1.95) | ||||
| TT vs TC | 0.06 | 0.59(0.34-1.01) | ||||
| Dominent model | 0.18 | 0.27 | 1.22(0.86-1.74) | |||
| Recessive model | 0.11 | 0.13 | 0.66(0.39-1.12) |
P 1 from χ 2 test, P 2 from Logistic regression analysis and adjusted for age, gender, Dominant Model TT + AT compared with AA, Recessive Model AA + AT compared with TT for rs926672, Dominant Model TT + TC compared with CC, Recessive Model CC + TC compared with TT for rs2057077, OR odds ratio, CI confidence interval