Table 1.
Characteristics of the FACT-G and QLQ-C30 Data Sets
| FACT-G Data Set |
QLQ-C30 Data Sets |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| (n = 530) |
All (n = 771) |
Breast (n = 100) |
Lung (n = 99) |
Multiple Myeloma (n = 572) |
||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
| Age, y | 59.01 | 11.92 | 68.31 | 9.56 | 53.9 | 10.94 | 62.73 | 10.5 | 71.79 | 5.45 |
| Male, % | 51.7 | 44.1 | 0.0 | 48.0 | 50.0 | |||||
| EQ-5D-3L | ||||||||||
| EQ-5D utility value | 0.721 | 0.22 | 0.58 | 0.342 | 0.765 | 0.20 | 0.742 | 0.20 | 0.519 | 0.36 |
| EQ-5D = 1, % | 17.5 | 10.7 | 24.0 | 17.1 | 7.9 | |||||
| Range of EQ-5D-3L | −0.135 to 1 | −0.594 to 1 | −0.144 to 1 | 0.088 to 1 | −0.594 to 1 | |||||
| FACT-G | ||||||||||
| Physical | 20.16 | 5.70 | — | — | — | — | — | — | — | — |
| Social | 22.68 | 4.77 | — | — | — | — | — | — | — | — |
| Emotional | 17.50 | 4.46 | — | — | — | — | — | — | — | — |
| Functional | 17.58 | 5.86 | — | — | — | — | — | — | — | — |
| Total score | 77.92 | 15.16 | — | — | — | — | — | — | — | — |
| EORTC QLQ-C30 | ||||||||||
| Physical functioning | — | — | 64.81 | 25.59 | 78.27 | 19.87 | 69.76 | 19.62 | 61.6 | 26.5 |
| Role functioning | — | — | 59.14 | 33.18 | 72.67 | 27.68 | 67.51 | 26.98 | 55.33 | 34.17 |
| Emotional functioning | — | — | 69.71 | 24.91 | 73 | 22.69 | 76.26 | 21.47 | 68.01 | 25.61 |
| Cognitive functioning | — | — | 76.05 | 22.74 | 76.83 | 22.83 | 77.27 | 20.54 | 75.7 | 23.11 |
| Social functioning | — | — | 69.13 | 29.82 | 72 | 26.15 | 73.74 | 23.82 | 67.83 | 31.25 |
| Fatigue‡ | — | — | 45.42 | 26.16 | 39.11 | 20.86 | 42.87 | 23.11 | 46.97 | 27.3 |
| Nausea‡ | — | — | 9.014 | 17.87 | 11 | 19.85 | 10.27 | 16.79 | 8.45 | 17.69 |
| Pain‡ | — | — | 40.4 | 32.99 | 23 | 24.25 | 22.56 | 23.49 | 46.53 | 33.54 |
| Dyspnea‡ | — | — | 24.73 | 28.97 | 16.67 | 22.47 | 36.7 | 30.67 | 24.07 | 29.09 |
| Sleep disturbance‡ | — | — | 32.68 | 32.6 | 34 | 31.06 | 30.98 | 28.27 | 32.75 | 33.59 |
| Appetite loss‡ | — | — | 27.37 | 32.53 | 19.67 | 28.46 | 28.62 | 32.3 | 28.5 | 33.1 |
| Constipation‡ | — | — | 23.13 | 30.71 | 11.67 | 23.39 | 22.9 | 29.98 | 25.17 | 31.56 |
| Diarrhea‡ | — | — | 9.511 | 19.86 | 15.67 | 26.99 | 11.45 | 20.29 | 8.1 | 18.04 |
| Financial impact‡ | — | — | 19.76 | 28.78 | 23.67 | 30.45 | 22.9 | 28.83 | 18.53 | 28.42 |
| Global quality of life | — | — | 52.76 | 23.18 | 67.92 | 18.17 | 62.12 | 21.04 | 48.48 | 22.75 |
For FACT-G, higher scores indicate better well-being and quality of life. The EORTC QLQ-C30 dimension score ranges from 0 to 100; higher scores indicate better functioning and quality of life.
FACT-G, Functional Assessment of Cancer Therapy—General Scale; QLQ-C30, European Organization for Research and Treatment Quality of Life Questionnaire Core 30.
‡
Higher scores for symptom scales indicate worse symptoms.