Table 1.
Top 10 GWAS SNPs which are associated with senDMP signature ordered by absolute chi-squared statistic
| SNP ID | CHR | Position | Gene | RAL | Trait | Cor | Stat |
|---|---|---|---|---|---|---|---|
| rs10496584 | 2 | 123126479 | Intergenic | A | Lentiform nucleus volume | 0.885 | −424 |
| rs4848768 | 2 | 123141545 | Intergenic | B | Lentiform nucleus volume | −0.865 | −403 |
| rs12716852 | 16 | 78188738 | WWOX | A | Pulmonary function | 0.896 | −375 |
| rs17041 | 6 | 108853493 | LACE1 | B | Obesity-related traits | 0.927 | 369 |
| rs7944584 | 11 | 47336320 | MADD | A | Fasting glucose-related traits (interaction with BMI) | 0.909 | −354 |
| rs2989476 | 1 | 61059259 | NFIA | A | Bipolar disorder | −0.888 | 338 |
| rs966423 | 2 | 218310340 | DIRC3 | A | Thyroid cancer | 0.869 | −338 |
| rs4527850 | 8 | 134196849 | WISP1 | A | Type 2 diabetes | 0.839 | −327 |
| rs4432842 | 5 | 57172078 | Intergenic | B | Birth weight | 0.810 | 326 |
| rs2479106 | 9 | 126525212 | NR | B | Polycystic ovary syndrome | 0.860 | 326 |
Cor: Pearson’s correlation coefficient between the SNP and the senDMPs; RAL: risk allele for the SNP; Stat: the directional chi-squared statistic