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. 2015 Sep 17;5:55. doi: 10.1186/s13578-015-0046-6

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© Alhadlaq et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Zinc ferrite NPs induced cytotoxicity in A431, HepG2 and A549 cells through ROS generation. Cells were exposed to zinc ferrite NPs at a concentration of 20 µg/ml in the presence of 10 mM N-acetyl-cystein (NAC) for 24 h. At the end of the exposure time, cell viability was determined. We observed that NAC significantly preserved the viability of all three cells induced by zinc ferrite NPs. Data represented are mean ± SD of three identical experiments made in three replicate. *Significant difference as compared to the controls (p < 0.05 for each). ^#Significant inhibitory effect of NAC on cell viability reduction (p < 0.05 for each)