Fig. 2.
MSC transplantation decreases IOP in a rat model of ocular hypertension. The intraocular pressure (IOP) was monitored in both cauterized (right eye (RE)) and noncauterized (left eye (LE)) eyes. IOP measurements of the RE were reported for each animal per group: hypertensive eyes injected with 5 × 105 MSCs (EVC + MSCs, green bar; n = 12), hypertensive eyes injected with culture medium alone (EVC + MEM, red bar; n = 10), or normotensive eyes injected with 5 × 105 MSCs (MSCs, black bar; n = 5) a. Individual average of delta IOP (ΔIOP = RE IOP − LE IOP) measurements from injection to sacrifice times were calculated and compared between the EVC + MSCs and EVC + MEM groups b *fp <0.05, **p <0.05, ***p <0.001 vs. EVC + MEM. dMSCs differentiated mesenchymal stem cells, EVC episcleral vein cauterization, MEM minimum essential medium, MSCs mesenchymal stem cells