Fig 4. The segregation pattern of rs76418789 in the pedigree.

The results from PCR sequencing of rs76418789 were placed on each member in the pedigree. The arrowheads indicated the SNV portion. Red colored variants were derived from the mother’s risk allele, whereas green colored ones were derived from father’s reference allele. The pedigree comprised healthy parents (father is indicated as ‘1’ and mother as ‘2’), a healthy second son (4), and older (3) and younger sons (5) affected by Crohn’s disease. Age is indicated in years (y) in the right margin.