Table 2.
Recruited controls (n = 48) | Recruited 22q11 carriers (n = 44) | Non-recruited 22q11 carriers (n = 92) | |
---|---|---|---|
Mean age (age span) | 20.3 (12–48) | 20.3 (12–48) | 22.6(12–54) |
Male:female ratio | 28: 20 | 25:19 | 41:51 |
Caucasian ancestry a | 47 | 44 | n.a. |
3 megabase deletion (%) | 0 (0 %) | 41 (93 %) | n.a. |
Segregation (%) | 0 (0 %) | 5 (11 %) | 4 (4 %) |
RIST general intelligence (S.D)b | 107.7 (11.1) | 78.9 (17.4) | n.a. |
Diagnoses % (current state disorder)c | |||
Alcohol and psychoactive substance dependence | 0 (0) | 0(0) | 1.6(n.a.) |
Schizophrenia Spectrum disorders | 0 (0) | 0(0) | 0 (n.a.) |
Affective disorders | 0 (0) | 7 (4.5) | 4.3(n.a.) |
Anxiety and Fobia | (1) 9.1 | 11 (18.2) | 8.7(n.a) |
Anorexia | 0(0) | 0(0) | 0 (n.a) |
Intellectual disability | 0 (n.a) | 34 (n.a) | 29.3(n.a) |
Autism | 0(n.a) | 11 (n.a) | 6.5(n.a) |
ADHD | 0 (0) | 9 (11.4) | 8.7(n.a) |
n.a not assessed
aOne control subject had Asian ancestry
bIQ scores are derived from the Reynolds Intellectual Screening Test (RIST) using pre-access to an updated raw- to T-score table kindly provided by the publisher (in submission)
cPercentages in () represents current diagnostics obtained from the M.I.N.I or M.I.N.I-kid diagnostic interviews