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. 2015 Sep 17;14:351. doi: 10.1186/s12936-015-0883-0

Table 2.

Median survival time and 95 % confidence interval per experiment

Hours/experiment 24 h (1 d) 72 h (3 d) 120 h (5 d) 168 h (7 d) 240 h (10 d) 336 h (14 d) 504 h (21 d)
Exp. 1 control 216 [168, 264] 144 [96, 192] 168 [144, 192] 96 [48, 216] n/a 156 [96, 192] 120 [96, 168]
0.2 mg/Kg OE 192 [144, 264] 72 [72, 96] 120 [96, 168] 192 [168, 192] n/a 24 [24, 96] 96 [96, 120]
0.5 mg/Kg OE 24 [24, 24] 48 [48, 72] 72 [72, 96] 168 [120, 216] n/a 24 [24, 72] 96 [96, 96]
0.5 mg/Kg TE 48 [48, 72] 72 [48, 72] 48 [48, 72] 72 [72, 96] n/a 48 [48, 72] 96 [96, 120]
Exp. 2 control 144 [120, 168] 72 [48, 120] 216 [168, 288] 240 [216, 264] n/a 192 [168, 192] 120 [120, 120]
0.1 mg/Kg OI 96 [72, 96] 48 [48, 72] 132 [48, 264] 144 [96, 240] n/a 192 [168, 216] 120 [120, 144]
0.2 mg/Kg OI 72 [72, 72] 60 [48, 72] 72 [72, 120] 144 [96, 168] n/a 168 [144, 216] 120 [120, 120]
0.75 mg/Kg TE 48 [48, 48] 48 [24, 48] 48 [48, 48] 48 [48, 72] n/a 168 [144, 192] 120 [120, 120]
Exp.3 control n/a1 [−∞, ∞] n/a n/a 216 [216, 240] 168 [144, 168] 192 [192, 240] n/a1 [240, ∞]
1.5 mg/Kg TE 24 [24, 24] n/a n/a 48 [24, 48] 72 [48, 96] 192 [192, 240] n/a1 [216, ∞]
1.0 mg/Kg OF 24 [24, 24] n/a n/a 48 [48, 48] 72 [72, 96] 132 [72, 192] 144 [72, 240]
1.5 mg/Kg OF 24 [24, 24] n/a n/a 24 [24, 48] 48 [24, 48] 84 [48, 144] 72 [48, 168]
Exp. 4 control 144 [120, 144] 168 [168, 216] n/a 192 [168, 240] n/a n/a1 [216, ∞] 240 [216, ∞]
0.25 mg/Kg OF 48 [48, 48] 120 [96, 144] n/a 48 [48, 48] n/a 204 [144, ∞] 216 [192, ∞]
0.5 mg/Kg OF 48 [48, 72] 120 [120, 144] n/a 144 [144, 168] n/a 216 [144, ∞] n/a1 [216, ∞]

Values in square brackets represent the 95 % confidence intervals for the estimated median lethal time; n/a, time point not tested; n/a1, denotes estimate nor applicable because the survival function did not reach 0.5, therefore there is not a median value estimate; ∞, infinity, the survival function did not reach the corresponding to 95 % limit value

h hours, d days, Exp. experiment, OE oral eprinomectin, TE topical eprinomectin, OI oral ivermectin, OF oral fipronil