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. 2015 Sep 17;12:176. doi: 10.1186/s12974-015-0399-0

Fig. 3.

Fig. 3

Cytokine protein levels in proximal optic nerve (pON). Anti-inflammatory FGF-2 and pro-inflammatory IL-6 and MIP-1α levels were lower in the pON of young DBA/2J mice than all other groups. Pro-inflammatory IL-12 was only elevated in pON of young and middle-aged DBA/2J mice. Asterisk indicates that D3–5 mice have significantly lower cytokine levels than D2G controls and D8–10 and D12–15 pON. Number sign indicates significance greater than bracketed comparison (p < 0.05). Arrows indicate values below limits of detection for the assay. Error bars depict standard error of the mean