Table 3.
Resistance and decreased susceptibility to cefixime (CFM) or ceftriaxone (CRO) in Neisseria gonorrhoeae isolates cultured from 1995 to 2005 in Kanagawa area, Japan
| Year | Number of isolatesa | CFM-DSa,b | CFM-Ra,c | CRO-DSa,b | |||
|---|---|---|---|---|---|---|---|
| No.a | % | No.a | % | No.a | % | ||
| 1995 | 34 (1) | 1 (1) | 2.9 | 1 (0) | 2.9 | 0 | 0 |
| 1996 | 70 (0) | 0 | 0 | 0 | 0 | 0 | 0 |
| 1997 | 88 (1) | 0 | 0 | 1 (1) | 1.1 | 0 | 0 |
| 1998 | 89 (84) | 0 | 0 | 5 (5) | 5.6 | 0 | 0 |
| 1999 | 69 (50) | 2 (2) | 2.9 | 3 (3) | 4.3 | 0 | 0 |
| 2000 | 54 (49) | 6 (5) | 11.1 | 6 (5) | 11.1 | 1 (1) | 1.9 |
| 2001 | 102 (90) | 10 (9) | 9.8 | 34 (32) | 33.3 | 17 (17) | 16.7 |
| 2002 | 21 (21) | 0 | 0 | 12 (12) | 57.1 | 4 (4) | 19.0 |
| 2003 | 55 (27) | 5 (4) | 9.1 | 26 (23) | 47.3 | 16 (14) | 29.1 |
| 2004 | 74 (34) | 10 (10) | 13.5 | 29 (24) | 39.2 | 16 (13) | 21.6 |
| 2005 | 34 (15) | 8 (6) | 23.5 | 10 (9) | 29.4 | 5 (5) | 14.7 |
aNumber of isolates examined genetically is given in parentheses
bMIC = 0.125 mg/L of cefixime or ceftriaxone
cMIC > 0.125 mg/L of cefixime