Table 2.
Baseline and resuscitation data according to age, sex, and treatment
| Group | Treatment | Numbera | Age, week | Body weight, g | Epinephrine dose, μg/g body weight | Epinephrine dose, g | CPR time, s | Survival rate, % |
|---|---|---|---|---|---|---|---|---|
| Young male | VEH | 15 | 11.1 (0.4) | 25.0 (1.6) | 0.53 (0.09) | 13.2 (2.0) | 129 (29) | 68 |
| EST | 15 | 11.2 (0.4) | 25.1 (1.8) | 0.51 (0.11) | 12.7 (2.2) | 118 (37) | 68 | |
| P * | 0.90 | 0.97 | 0.09 | 0.71 | 0.42 | 1 | ||
| Young female | VEH | 14 | 12.5 (2.0) | 19.7 (0.8) | 0.75 (0.08) | 14.8 (1.6) | 158 (28) | 64 |
| EST | 14 | 12.9 (1.7) | 19.9 (1.1) | 0.71 (0.11) | 14.0 (1.9) | 151 (33) | 88 | |
| P * | 0.58 | 0.94 | 0.99 | 0.42 | 0.75 | 0.10 | ||
| Aged male | VEH | 8 | 83.8 (2.9) | 34.9 (6.8) | 0.42 (0.10) | 14.3 (1.9) | 136 (36) | 71 |
| EST | 10 | 82.6 (3.1) | 39.2 (8.6) | 0.36 (0.09) | 13.6 (1.5) | 138 (27) | 67 | |
| P * | 0.26 | 0.26 | 0.11 | 0.33 | 0.87 | 0.60 | ||
| Aged female | VEH | 9 | 81.4 (2.4) | 29.1 (5.1) | 0.51 (0.13) | 14.2 (1.9) | 142 (35) | 100 |
| EST | 10 | 82.2 (1.4) | 31.1 (4.3) | 0.42 (0.09) | 12.9 (2.1) | 130 (35) | 83 | |
| P * | 0.38 | 0.33 | 0.11 | 0.16 | 0.44 | 0.49 |
Data are presented as mean (standard deviation)
CPR Cardiopulmonary resuscitation, VEH vehicle, EST 17β-estradiol
anumber of survives
*P values shown for Sidak’s multiple comparison test or chi-squared test when appropriate