Unsupervised heat maps of all identified metabolites and their associated fold changes in Brg1/Brm double-mutant hearts compared to a
Control Group 1 (Brg1floxed/floxed; αMHC-Cre-ERT+/0; Brm−/− minus tamoxifen treatment), b
Control Group 2 (Brg1floxed/floxed; αMHC-Cre-ERT0/0(no transgene); Brm−/− mice plus tamoxifen treatment), and c Combined Groups 1 & 2 controls. d Identification of the VIP significant metabolites (p<0.05). N = 8 (Brg1/Brm double mutant hearts), N = 3 (Control Group 1), N = 3 (Control Group 2), N = 6 (Control Groups 1 & 2) hearts per group analyzed