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. 2015 Aug 28;16(1):180. doi: 10.1186/s13059-015-0741-y

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© Fortin and Hansen. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 17 — scWGBS data. Depicted are data from experiments on mESCs. a Estimated compartments using the HiC-mESC-2012 data on chromosome 12 at a resolution of 100 kb. b Estimated compartments using scWGBS data from 20 mESCs grown on serum. c The first eigenvector of a correlation matrix obtained using scWGBS data from 12 ovulated metaphase II (MII) oocytes. d Density of correlations for data on mESCs and MII cells; compartments are estimated using the HiC-mESC-2012 data. The two cell types have very different patterns. e Genome-wide methylation for 20 mESCs and 12 ovulated MII oocytes. Substantial heterogeneity is observed for the former but not the latter