Table 1.
Corn oil control | 400 mg/kg MTBE |
1000 mg/kg MTBE |
2000 mg/kg MTBE |
|
---|---|---|---|---|
Absolute weight (g) | ||||
Final body weight | 42.3 ± 1.90 | 41.8 ± 2.21 | 42.3 ± 2.02 | 42.2 ± 2.09 |
Testes | 0.255 ± 0.033 | 0.242 ± 0.023 | 0.278 ± 0.022 | 0.248 ± 0.031 |
Epididymides | 0.108 ± 0.008 | 0.110 ± 0.008 | 0.111 ± 0.009 | 0.116 ± 0.006 |
Seminal vesicles | 0.302 ± 0.067 | 0.321 ± 0.081 | 0.308 ± 0.037 | 0.326 ± 0.045 |
Liver | 2.24 ± 0.236 | 2.26 ± 0.215 | 2.15 ± 0.281 | 2.12 ± 0.213 |
Brain | 0.490 ± 0.023 | 0.507 ± 0.021 | 0.509 ± 0.226 | 0.509 ± 0.023 |
Ratio of organ:final body weight (%) | ||||
Testes | 0.60 ± 0.06 | 0.58 ± 0.06 | 0.66 ± 0.05 | 0.59 ± 0.06 |
Epididymides | 0.25 ± 0.02 | 0.27 ± 0.02 | 0.26 ± 0.03 | 0.28 ± 0.01 |
Seminal vesicles | 0.71 ± 0.15 | 0.78 ± 0.23 | 0.73 ± 0.08 | 0.77 ± 0.08 |
Liver | 5.30 ± 0.55 | 5.44 ± 0.62 | 5.08 ± 0.58 | 5.01 ± 0.39 |
Brain | 1.16 ± 0.04 | 1.21 ± 0.07 | 1.21 ± 0.07 | 1.21 ± 0.06 |
Notes: Gavage treatment consisted of MTBE in corn oil on days 1, 3, and 5 at doses of 0 (vehicle only), 400, 1000 or 2000 mg/kg MTBE, n=6. 2.5 IU/g body weight hCG was administered ip on day 6 and necropsy was on day 7. Values in the table are mean ± standard deviation. No significant differences were observed across the groups (p>0.05).