Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Quality of life
Systematic review	Women with menorrhagia, total number of women randomised not reported Data from 1 RCT	Health-related quality-of-life scores 1 year with progestogen-releasing IUD (levonorgestrel) with hysterectomy Absolute results not reported	Reported as not significant		Not significant
RCT	236 women	Change from baseline to 10-year follow-up in EQ-5D –1.10 with levonorgestrel IUD –0.01 with hysterectomy	P = 0.94		Not significant
RCT	236 women	Change from baseline to 10-year follow-up in RAND-36 General health –2.3 with levonorgestrel IUD –4.5 with hysterectomy	P = 0.39 The RCT also tested 7 other individual items of the RAND-36 scale and there was no significant difference between groups		Not significant
RCT	236 women	Change from baseline to 10-year follow-up in general health (visual analogue scale [VAS] 0–100) –4.4 with levonorgestrel IUD –7.4 with hysterectomy	P = 0.32		Not significant
RCT	72 women with heavy menstrual bleeding unresponsive to medical treatment	SF-36 General health 24 months 87.4 with progestogen-releasing IUD 88.2 with laparoscopic supracervical hysterectomy	P = 0.115		Not significant
RCT	72 women with heavy menstrual bleeding unresponsive to medical treatment	SF-36 Physical functioning 24 months 85.3 with progestogen-releasing IUD 90.3 with laparoscopic supracervical hysterectomy	P = 0.350		Not significant
RCT	72 women with heavy menstrual bleeding unresponsive to medical treatment	SF-36 Role function emotional 24 months 83.5 with progestogen-releasing IUD 67.4 with laparoscopic supracervical hysterectomy	Reported as P = 0.000	Effect size not calculated	progestogen-releasing IUD
RCT	72 women with heavy menstrual bleeding unresponsive to medical treatment	SF-36 Mental health 24 months 85.3 with progestogen-releasing IUD 48.5 with laparoscopic supracervical hysterectomy	Reported as P = 0.000	Effect size not calculated	progestogen-releasing IUD
RCT	72 women with heavy menstrual bleeding unresponsive to medical treatment	SF-36 Social functioning 24 months 89.4 with progestogen-releasing IUD 87.6 with laparoscopic supracervical hysterectomy	P = 0.125		Not significant
RCT	72 women with heavy menstrual bleeding unresponsive to medical treatment	SF-36 Vitality 24 months 78.8 with progestogen-releasing IUD 73.2 with laparoscopic supracervical hysterectomy	P = 0.570		Not significant