Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Quality of life
Systematic review	Women with menorrhagia 3 RCTs in this analysis	Overall scores or individual dimensions of the Short Form-36 (SF-36) with progestogen-releasing IUD with endometrial ablation Absolute results not reported	Reported as not significant P value not reported		Not significant
Systematic review	Women with menorrhagia 2 RCTs in this analysis	SF-36 score (Mental health) 1 year with progestogen-releasing IUD with endometrial ablation Absolute results not reported	Mean difference 6.60 95% CI 0.55 to 12.65	Effect size not calculated	endometrial ablation
Systematic review	Women with menorrhagia 2 RCTs in this analysis	SF-36 score (Vitality) 1 year with progestogen-releasing IUD with endometrial ablation Absolute results not reported	Mean difference +2.10 95% CI –3.89 to +8.10		Not significant
Systematic review	Women with menorrhagia 2 RCTs in this analysis	SF-36 score (Physical role limitation) 1 year with progestogen-releasing IUD with endometrial ablation Absolute results not reported	Mean difference +2.33 95% CI –5.65 to +10.31		Not significant
Systematic review	Women with menorrhagia 2 RCTs in this analysis	SF-36 score (Emotional role limitation) 1 year with progestogen-releasing IUD with endometrial ablation Absolute results not reported	Mean difference 10.30 95% CI 2.15 to 18.46	Effect size not calculated	endometrial ablation
Systematic review	Women with menorrhagia 2 RCTs in this analysis	SF-36 score (Social functioning) 1 year with progestogen-releasing IUD with endometrial ablation Absolute results not reported	Mean difference +4.48 95% CI –2.13 to +11.08		Not significant
Systematic review	Women with menorrhagia Data from 1 RCT	SF-36 score (General health) 2 years with progestogen-releasing IUD with endometrial ablation Absolute results not reported	Mean difference –2.60 95% CI –11.18 to +5.98		Not significant