Skip to main content
. 2015 Sep 17;10(9):e0138487. doi: 10.1371/journal.pone.0138487

Fig 5. Redox state changes in primary human hepatocytes treated with ximelagatran.

Fig 5

A. Effect of ximelagatran treatment on the cell viability (cellular ATP content) and the cellular GSH (B) and GSH:GSSG ratio (C) in PHHs derived from three different donors. D. Analysis of the redox state of mitochondrial-specific Trx2 in control- and ximelagatran-treated PHHs by redox Western blotting. Densitometric analysis of the fractions of different Trx2 redox forms is shown on the right panel. Data are representative for one donor. *, p<0.05; **, p<0.01: ***, p<0.001.