Fig 3. Changes in corneal edema and opacity after chemical corneal endothelial injury in rabbits.

A. Corneal edema increases 1 day after injury compared to the control, and then decreases over time; however, corneal opacity does not revert back to levels observed in control rabbits at day 14. Corneal edema decreases from the periphery, and peripheral and central corneas are edematous at day 1 and at day 7. At day 14, the central cornea is edematous (white arrow), while the periphery is transparent (black arrow). B. CCT increases significantly at day 1 and at day 7 after injury compared to the control (p = 0.045 and p = 0.015). CCT generally decreases over time and there are no differences in CCT at day 14 compared to the control, although CCT does not revert to levels observed in control rabbits. * Statistically significant by Student’s t-test