Table 2.
Gene | First author’s name (year) | Cases
|
Controls
|
HWE of control (P-value) | Frequency of 1G allele in controls | Quality* | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | 2G/2G | 1G/2G | 1G/1G | 2G | 1G | N | 2G/2G | 1G/2G | 1G/1G | 2G | 1G | |||||
MMP1–1607 | Matsumura et al20 (2004) | 215 | 101 | 88 | 26 | 290 | 140 | 166 | 88 | 61 | 17 | 237 | 95 | Y (0.1953) | 0.713855 | 7 |
1G/2G | Jin et al19 (2005) | 183 | 112 | 51 | 20 | 275 | 91 | 350 | 194 | 105 | 51 | 493 | 207 | N (0.0000) | 0.704286 | 7 |
Fang et al18 (2010) | 246 | 155 | 85 | 6 | 395 | 97 | 252 | 161 | 78 | 13 | 400 | 104 | Y (0.3826) | 0.793651 | 7 | |
Devulapalli et al16 (2014) | 166 | 46 | 114 | 6 | 206 | 126 | 202 | 50 | 130 | 22 | 230 | 174 | N (0.0000) | 0.569307 | 7 | |
Dey et al17 (2014) | 145 | 56 | 66 | 23 | 178 | 112 | 145 | 53 | 72 | 20 | 178 | 112 | Y (0.2713) | 0.613793 | 6 | |
Hua et al4 (2014) | 422 | 186 | 187 | 49 | 559 | 285 | 428 | 158 | 195 | 75 | 511 | 345 | Y (0.5686) | 0.596963 | 7 |
Note:
Represents the confidence of the study.
Abbreviations: MMP1, matrix metalloproteinase-1; HWE, Hardy–Weinberg equilibrium; N, number of subjects.