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. 2015 Sep 10;8:2519–2526. doi: 10.2147/OTT.S83004

Table 2.

Sample sizes and MMP1–1607 1G>2G allele and genotype distributions in the studies considered in the present meta-analysis

Gene First author’s name (year) Cases
Controls
HWE of control (P-value) Frequency of 1G allele in controls Quality*
N 2G/2G 1G/2G 1G/1G 2G 1G N 2G/2G 1G/2G 1G/1G 2G 1G
MMP1–1607 Matsumura et al20 (2004) 215 101 88 26 290 140 166 88 61 17 237 95 Y (0.1953) 0.713855 7
1G/2G Jin et al19 (2005) 183 112 51 20 275 91 350 194 105 51 493 207 N (0.0000) 0.704286 7
Fang et al18 (2010) 246 155 85 6 395 97 252 161 78 13 400 104 Y (0.3826) 0.793651 7
Devulapalli et al16 (2014) 166 46 114 6 206 126 202 50 130 22 230 174 N (0.0000) 0.569307 7
Dey et al17 (2014) 145 56 66 23 178 112 145 53 72 20 178 112 Y (0.2713) 0.613793 6
Hua et al4 (2014) 422 186 187 49 559 285 428 158 195 75 511 345 Y (0.5686) 0.596963 7

Note:

*

Represents the confidence of the study.

Abbreviations: MMP1, matrix metalloproteinase-1; HWE, Hardy–Weinberg equilibrium; N, number of subjects.