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. 2015 Mar 25;80(3):569–580. doi: 10.1111/bcp.12640

Table 5.

Statistical analysis of pharmacokinetic parameters in adolescents - formoterol

Formoterol BDP/FF pMDI vs.BDP pMDI+FF pMDI BDP/FF pMDI with VHC vs.BDP pMDI+FF pMDI BDP/FF pMDI with VHC vs.BDP/FF pMDI
PE (90% CI) PE (90% CI) PE (90% CI)
Cmax 1.00 (0.82, 1.22) 1.68 (1.38, 2.05) 1.68 (1.38, 2.06)
AUC(0,0.5 h) 0.97 (0.74, 1.20) 1.71 (1.39, 2.10) 1.76 (1.43, 2.15)
AUC(0,t) 0.95 (0.86, 1.05) 1.02 (0.93, 1.13) 1.08 (0.97, 1.19)

PE, Point estimate calculated as ratio of the adjusted geometric means for the different PK parameters between treatments