. Author manuscript; available in PMC: 2016 Jan 31.

Published in final edited form as: Cancer Lett. 2014 Nov 15;357(1):160–169. doi: 10.1016/j.canlet.2014.11.020

Table 1. Bone morphometric parameters of contralateral non–tumor-injected tibiae of vehicle and TH-302 treated animals.

Trabecular bone volume (BV), bone surface (B.S.), intersection surface (i.S.), trabecular space (Tb.Sp.), trabecular number (Tb.N.), trabecular thickness (Tb.Th.), trabecular pattern factor (Tb.Pf.) and structure model index (SMI) were measured by three dimensional analysis of μCT images of trabecular bone only. Results are expressed as mean ± SE. Significance of results is with respect to untreated animals obtained using Student’s t test.

Parameters	BTK-143				K-HOS
	Vehicle control		TH-302		Vehicle control		TH-302
	Mean	SE	Mean	SE	Mean	SE	Mean	SE
BV(mm³)	2.87	0.10	2.82	0.07	2.87	0.10	2.82	0.07
B.S. (mm²)	76.21	4.07	74.46	4.89	76.21	4.07	74.46	4.89
i.S. (mm²)	2.16	0.66	2.58	0.66	2.16	0.66	2.58	0.66
Tb.Sp. (mm)	26.63	1.66	26.24	1.53	0.39	0.02	0.49	0.02
Tb.N. (1/mm)	2.08	0.14	1.72	0.17	2.08	0.14	1.72	0.17
Tb.Th. (mm)	0.06	0.00	0.06	0.00	0.06	0.00	0.06	0.00
Tb.Pf. (1/mm)	15.35	2.93	13.57	3.16	0.22	1.18	0.21	2.32
SMI	2.02	0.08	2.09	0.07	2.02	0.08	2.09	0.07