. Author manuscript; available in PMC: 2015 Sep 18.

Published in final edited form as: J Am Soc Hypertens. 2013 Feb 19;7(2):170–179. doi: 10.1016/j.jash.2013.01.003

Table 1.

Previous study methods and thresholds for establishing salt sensitivity

Study	Method (Sodium/Day)	Salt Sensitivity Definition	Results (% of Subjects Salt-sensitive)
Morris RC⁶ (Normotensives)	15 mmol/70 kg (2 weeks) → 250 mmol/70 kg (1 week)	⊿ MAP ≥3 mm Hg	Blacks – 79% Whites – 36%
Kawasaki T³ (Hypertensives)	9 mmol (1 week) → 249 mmol (1 week)	⊿ MAP >10%	47%
Weinberger MH⁴	2L NS (308 mmol) (1 day) → 10 mmol and furosemide (1 day)	⊿ MAP ≥10 mm Hg	Normotensive – 26% Hypertensive – 51% Black normotensive – 36% Black hypertensive – 73%
Obarzanek E⁵	140 mmol (1 month) → 62 mmol (1 month) AND 104 mmol (1 month) → 62 mmol (1 month)	⊿ SBP >6.4 mm Hg AND ⊿ SBP >3.4 mm Hg	Normotensive – 20% Hypertensive – 41%
Wright JT⁸ (Women)	20 mmol → 200 mmol (1 week)	⊿ MAP ≥10 mm Hg	Black normotensive – 43% White normotensive – 50% Black hypertensive – 64% White hypertensive – 52%

MAP, mean arterial pressure.