Figure 8.
Effect of adenosine receptor antagonists on pollen-induced increase in physical barrier properties of airway epithelial cells. Polarized 16HBEs were pre-treated for 60 min with A2A and A2B adenosine receptor antagonists and subsequently exposed to pollen extract (PE) equivalent of 5 mg/ml pollen. Physical barrier properties were monitored by TER measurements over time (A). As control, adenosine and receptor antagonists were used and TER measurements after 24 h are shown (B). (n = 5); Mean ±SEM; *: p ≤ 0.05 compared to pollen or adenosine treatment (paired Student's t-test)