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. 2015 Sep 17;10(9):e0136276. doi: 10.1371/journal.pone.0136276

Fig 6. Ranking of serial biopsy sections for degree of tubular injury and immunohistochemistry staining.

Fig 6

Serial sections of protocol and DGF biopsies were stained for NTT-MMP-2 and FL-MMP-2 with hematoxylin/eosin and ranked according to injury score. Representative results for injury score 3. (A, B, C X 300; D, E, F X 600). There is a correlation between the overall tubular injury scale and the immunohistochemical staining scales for both NTT-MMP-2 and FL-MMP-2. Significantly, immunohistochemical staining for both NTT-MMP-2 and FL-MMP-2 occurs within the same tubular segments and there is a direct correlation between NTT-MMP-2 and FL-MMP-2 staining tubular injury.