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. 2015 Sep 17;10(9):e0136276. doi: 10.1371/journal.pone.0136276

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Fig 8 — Control protocol biopsies and DGF biopsies were processed for in situ hybridization to detect the NTT-MMP-2 mRNA transcript as detailed in Materials and Methods. Panel A: Control renal biopsy without the targeting NTT-MMP-2 oligonucleotides. Panel B: Control renal biopsy including the targeting NTT-MMP-2 oligonucleotides. There is no detectable NTT-MMP-2 transcript. Panel C: DGF biopsy without the targeting NTT-MMP-2 oligonucleotides. Panel D: DGF biopsy with the targeting NTT-MMP-2 oligonucleotides. There is readily detectable NTT-MMP-2 mRNA transcript signal within tubular epithelial cells (arrows). (Final magnification X 300).