Fig 3. Effects of chronic running exercise on the intra-peritoneal glucose tolerance test in Zucker diabetic fatty rats.
(A) Plasma glucose and (B) plasma insulin levels were measured by intra-peritoneal glucose tolerance test (IPGTT) at 4 days after the last exercise session and after 5 h of fasting in sedentary lean Zucker diabetic fatty (ZDF) rats (Sed-ZL), sedentary ZDF rats (Sed-ZDF) and aerobic treadmill exercised ZDF rats (Ex-ZDF) groups. (C) Homeostasis model assessment (HOMA) for insulin resistance (HOMA-IR), (D) HOMA for insulin sensitivity (HOMA-IS) and (E) HOMA for β-cell function (HOMA-β) were calculated by IPGTT data in Sed-ZL, Sed-ZDF and Ex-ZDF groups. Values are means ± SEM (n = 5/group). * p<0.05, ** p<0.01 compared with the Sed-ZL group; † p<0.05, †† p<0.01 compared with the Sed-ZDF group.