Table 1. Effects of chronic running exercise on plasma parameters, urine volume, urine parameters, and systolic blood pressure in Zucker diabetic fatty rats.
Sed-ZL | Sed-ZDF | Ex-ZDF | |
---|---|---|---|
Plasma | |||
Glucose (mg/dL) | 168 ± 18 | 458 ± 12** | 140 ± 7 †† |
Total cholesterol (mg/dL) | 76 ± 3 | 157 ± 6** | 123 ± 6** †† |
Triglycerides (mg/dL) | 47 ± 6 | 190 ± 16** | 165 ± 24** |
Free fatty acids (mEq/L) | 0.15 ± 0.01 | 0.29 ± 0.03** | 0.24 ± 0.01* |
Blood urea nitrogen (mg/dL) | 18.8 ± 1.0 | 26.3 ± 1.6** | 23.9 ± 1.0* |
Creatinine (mg/dL) | 0.29 ± 0.02 | 0.19 ± 0.01** | 0.20 ± 0.01** |
Urine | |||
Volume (mL/day) | 7.3 ± 1.3 | 37.1 ± 7.4* | 5.5 ± 0.7 † |
Uric acid (mg/day) | 1.5 ± 0.2 | 1.7 ± 0.7 | 0.9 ± 0.1 |
Albumin:creatinine ratio (mg/g Creatinine) | 50.4 ± 6.7 | 492.1 ± 69.9** | 176.4 ± 10.5 †† |
Creatinine clearance/body weight (mL/min per 100 g) | 5.5 ± 0.7 | 9.7 ± 1.4* | 4.5 ± 0.8 †† |
Hemodynamic data | |||
Systolic blood pressure (mmHg) | 148 ± 6 | 111 ± 3** | 112 ± 3** |
Sed-ZL, sedentary Zucker lean rats; Sed-ZDF, sedentary Zucker diabetic fatty rats; Ex-ZDF, treadmill exercised Zucker diabetic fatty rats.
* p < 0.05,
** p < 0.01 compared with Sed-ZL group.
† p < 0.05,
†† p < 0.01 compared with Sed-ZDF group.
Values are mean ± SEM (n = 5/group).