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. 2015 Sep 17;10(9):e0138037. doi: 10.1371/journal.pone.0138037

Table 1. Effects of chronic running exercise on plasma parameters, urine volume, urine parameters, and systolic blood pressure in Zucker diabetic fatty rats.

Sed-ZL Sed-ZDF Ex-ZDF
Plasma
 Glucose (mg/dL) 168 ± 18 458 ± 12** 140 ± 7 ††
 Total cholesterol (mg/dL) 76 ± 3 157 ± 6** 123 ± 6** ††
 Triglycerides (mg/dL) 47 ± 6 190 ± 16** 165 ± 24**
 Free fatty acids (mEq/L) 0.15 ± 0.01 0.29 ± 0.03** 0.24 ± 0.01*
 Blood urea nitrogen (mg/dL) 18.8 ± 1.0 26.3 ± 1.6** 23.9 ± 1.0*
 Creatinine (mg/dL) 0.29 ± 0.02 0.19 ± 0.01** 0.20 ± 0.01**
Urine
 Volume (mL/day) 7.3 ± 1.3 37.1 ± 7.4* 5.5 ± 0.7
 Uric acid (mg/day) 1.5 ± 0.2 1.7 ± 0.7 0.9 ± 0.1
 Albumin:creatinine ratio (mg/g Creatinine) 50.4 ± 6.7 492.1 ± 69.9** 176.4 ± 10.5 ††
 Creatinine clearance/body weight (mL/min per 100 g) 5.5 ± 0.7 9.7 ± 1.4* 4.5 ± 0.8 ††
Hemodynamic data
 Systolic blood pressure (mmHg) 148 ± 6 111 ± 3** 112 ± 3**

Sed-ZL, sedentary Zucker lean rats; Sed-ZDF, sedentary Zucker diabetic fatty rats; Ex-ZDF, treadmill exercised Zucker diabetic fatty rats.

* p < 0.05,

** p < 0.01 compared with Sed-ZL group.

p < 0.05,

†† p < 0.01 compared with Sed-ZDF group.

Values are mean ± SEM (n = 5/group).