Table 2.

Factors Associated with HDV Testing in Univariate Analyses (N=2,009)

Variable	Unadjusted OR (95% CI)	P value
Age (per 1 year increase)	0.99 (0.99–1.00)	0.49
White	1.2 (1.1–1.3)	<0.001
Male	1.8 (1.4–2.3)	<0.001
HBeAg tested	12.3 (9.1–12.2)	< 0.001
Anti-HBe tested	8.9 (7.8–10.0)	< 0.001
HBV DNA tested	3.8 ((3.5–4.2)	< 0.001
HCV Ab tested	2.2 (1.9–2.5)	< 0.001
HIV tested	2.6 (2.3–2.8)	< 0.001
HBcIgM tested	2.1 (1.9–2.3)	< 0.001
HBcIgM+	3.0 (2.6–3.5)	< 0.001
HBeAg+	1.7 (1.6–1.9)	< 0.001
HCV Ab+	0.86 (0.76–0.97)	0.014
Alcohol abuse	0.50 (0.45–0.55)	<0.001
Substance abuse	1.2 (1.0–1.3)	0.007
Cirrhosis	2.5 (2.2–2.8)	<0.001
High risk profile*	1.3 (1.1–1.5)	0.002
Oral nucleoside therapy	3.1 (2.9–3.4)	< 0.001
Interferon therapy	2.4 (1.9–3.1)	<0.001
Specialty care (GI/ID)	3.3 (3.0–3.6)	<0.001
Gastroenterology/Hepatology	4.0 (3.7–4.5)	<0.001
Infectious Disease	2.4 (2.1–2.7)	<0.001

Abbreviations: OR=odds ratio, CI=confidence interval, HBeAg= hepatitis B e antigen, Anti-HBe (hepatitis B antibody), HBV=hepatitis B virus, HCV=hepatitis C virus

Substance abuse, cirrhosis obtained using ICD-9-CM codes

Alcohol abuse = score of ≥5 on AUDIT-C questionnaire

Specialty care=at least 1 outpatient visit with gastroenterology or infectious disease specialist within 2 years of initial HBV diagnosis

^*High risk profile refers to patients with ALT ≥2 ULN and HBV DNA <2,000 IU/mL