Table 2.
Variable | Unadjusted OR (95% CI) | P value |
---|---|---|
Age (per 1 year increase) | 0.99 (0.99–1.00) | 0.49 |
White | 1.2 (1.1–1.3) | <0.001 |
Male | 1.8 (1.4–2.3) | <0.001 |
HBeAg tested | 12.3 (9.1–12.2) | < 0.001 |
Anti-HBe tested | 8.9 (7.8–10.0) | < 0.001 |
HBV DNA tested | 3.8 ((3.5–4.2) | < 0.001 |
HCV Ab tested | 2.2 (1.9–2.5) | < 0.001 |
HIV tested | 2.6 (2.3–2.8) | < 0.001 |
HBcIgM tested | 2.1 (1.9–2.3) | < 0.001 |
HBcIgM+ | 3.0 (2.6–3.5) | < 0.001 |
HBeAg+ | 1.7 (1.6–1.9) | < 0.001 |
HCV Ab+ | 0.86 (0.76–0.97) | 0.014 |
Alcohol abuse | 0.50 (0.45–0.55) | <0.001 |
Substance abuse | 1.2 (1.0–1.3) | 0.007 |
Cirrhosis | 2.5 (2.2–2.8) | <0.001 |
High risk profile* | 1.3 (1.1–1.5) | 0.002 |
Oral nucleoside therapy | 3.1 (2.9–3.4) | < 0.001 |
Interferon therapy | 2.4 (1.9–3.1) | <0.001 |
Specialty care (GI/ID) | 3.3 (3.0–3.6) | <0.001 |
Gastroenterology/Hepatology | 4.0 (3.7–4.5) | <0.001 |
Infectious Disease | 2.4 (2.1–2.7) | <0.001 |
Abbreviations: OR=odds ratio, CI=confidence interval, HBeAg= hepatitis B e antigen, Anti-HBe (hepatitis B antibody), HBV=hepatitis B virus, HCV=hepatitis C virus
Substance abuse, cirrhosis obtained using ICD-9-CM codes
Alcohol abuse = score of ≥5 on AUDIT-C questionnaire
Specialty care=at least 1 outpatient visit with gastroenterology or infectious disease specialist within 2 years of initial HBV diagnosis
High risk profile refers to patients with ALT ≥2 ULN and HBV DNA <2,000 IU/mL