Table 3.
Variable | Unadjusted (OR, 95% CI) | P value | Adjusted (OR, 95% CI) | P value |
---|---|---|---|---|
HCV Ab+ | 7.1 (4.4–11.5) | <0.001 | 3.2 (1.4–7.6) | 0.007 |
Alcohol abuse | 1.8 (1.1–2.8) | 0.016 | 3.2 (1.4–7.8) | 0.009 |
Cirrhosis | 2.4 (1.5–4.1) | 0.001 | 3.5 (1.4–8.5) | 0.006 |
High risk profile* | 4.2 (1.9–9.3) | <0.001 | 3.2 (1.4–7.5) | 0.007 |
HBcIgM+ | 0.21 (0.07–0.68) | 0.009 | 0.18 (0.02–1.5) | 0.107 |
HBeAg+ | 0.39 (0.21–070) | 0.002 | 0.50 (0.17–1.4) | 0.182 |
Substance abuse | 3.4 (2.1–5.4) | <0.001 | 2.0 (0.83–5.0) | 0.119 |
Interferon therapy | 2.7 (1.2–6.1) | 0.016 | 1.4 (0.27–7.1) | 0.693 |
Abbreviations HBcIgM = hepatitis b core IgM, HCV hepatitis c virus
Substance abuse, cirrhosis obtained using ICD-9-CM codes
Alcohol abuse = score of ≥5 on AUDIT-C questionnaire
High risk profile refers to patients with ALT ≥2 ULN and HBV DNA <2,000 IU/mL