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. 2015 Sep 18;10(9):e0138088. doi: 10.1371/journal.pone.0138088

Table 1. Background characteristics for Escherichia coli and Klebsiella pneumoniae isolates, ISIS-AR The Netherlands, 2008–2012.

E. coli K. pneumoniae
No. (%) No. (%) No. (%) No. (%) No. (%) No. (%)
blood isolates male urine isolates female urine isolates blood isolates male urine isolates female urine isolates
Variable n = 14461 n = 42270 n = 140782 n = 2492 n = 9995 n = 25553
ESC-R a 863 (6.0) 2481 (5.2) 5331 (3.6) 204 (8.2) 631 (6.3) 1000 (3.8)
Age in years
  19–64 4049 (28.0) 19379 (41.0) 69121 (47.3) 774 (31.1) 3169 (31.7) 8902 (33.5)
  ≥65 10412 (72.0) 27891 (59.0) 76992 (52.7) 1718 (68.9) 6826 (68.3) 17651 (66.5)
Gender b
  Female 7282 (50.4) - - - - 1087 (43.6) - - - -
  Male 7179 (49.6) - - - - 1405 (56.4) - - - -
Patient setting c
  GP - - 24244 (51.3) 89704 (61.4) - - 3702 (37.0) 14494 (54.6)
  OPD 4630 (32.0) 13045 (27.6) 29640 (20.3) 690 (27.7) 3728 (37.3) 6737 (25.4)
  IPD 8638 (59.7) 9558 (20.2) 25885 (17.7) 1515 (60.8) 2419 (24.2) 5042 (19.0)
  ICU 1186 (8.2) 423 (0.9) 884 (0.6) 287 (11.5) 146 (1.5) 280 (1.1)
Geographic Region
  Northwest 3727 (25.8) 15384 (32.5) 47351 (32.4) 618 (24.8) 2604 (26.1) 6440 (24.3)
  Northeast 1953 (13.5) 2200 (4.7) 5346 (3.7) 259 (10.4) 1420 (14.2) 4295 (16.2)
  Middle 2523 (17.4) 9991 (21.2) 31233 (21.4) 388 (15.6) 1559 (15.6) 4119 (15.5)
  Southwest 1814 (12.5) 7860 (16.7) 26901 (18.4) 347 (13.9) 1165 (11.7) 3316 (12.5)
  South 4423 (30.6) 11766 (24.9) 35018 (24.0) 873 (35.0) 3233 (32.3) 8358 (31.5)

aESC-R: Extended-spectrum cephalosporin-resistant

bUrine samples are stratified for gender.

cThe patient settings are: General Practitioner (GP), Outpatient Department (OPD), Inpatient Department (IPD) and Intensive Care Unit (ICU). The dataset did not contain blood isolates from general practitioners.