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. 2015 Sep 18;10(9):e0137053. doi: 10.1371/journal.pone.0137053

Table 2. Univariate analysis for 5-year overall and 5-year disease-free survival in 363 patients with colon cancer and only one lymph node metastasis.

Characteristics Patient Number 5-year survival rate P value 5-year disease-free P value
Age 0.061 0.835
 < 75 287 65.6% 52.2%
 ≧ 75 76 77.6% 61.4%
Gender 0.201 0.042
 Male 200 72.8% 56.7%
 Female 163 78.5% 68.2%
Performance Δ 0.999 0.426
 0~1 352 84.2% 77.1%
 2 11 78.2% 72.8%
Location Ψ 0.518 0.503
 Right 119 76.7% 61.4%
 Left 153 72.5% 60.8%
 Sigmoid 91 71.2% 52.3%
Differentiation 0.782 0.938
 Well 7 85.6% 72.5%
 Moderate 346 73.6% 59.1%
 Poor 9 84.7% 56.2%
Tumor depth 0.314 0.026
 T1+2 76 79.1% 72.4%
 T3+4 287 72.6% 54.7%
Invasion Ω 0.573 0.218
 Present 250 72.8% 58.1%
 Absent 113 73.3% 61.7%
CEA level < 0.001 < 0.001
 ≦5 251 81.2% 69.2%
 >5 112 54.6% 38.9%
LN sampling number 0.012 0.027
 ≧ 12 247 78.9% 68.3%
 < 12 116 64.6% 47.5%
Treatment 0.0692 0.150
Chemotherapy(-) 57 76.1% 78.7%
Chemotherapy(+) 306 73.2% 57.8%

Δ Performance status: according to the definition of ECOG-WHO

Ψ Location: Right: cecum to middle transverse colon, Left: middle transverse to descending colon.

Ω Invasion (present): if pathological report revealed one of venous, lympho-vessel or perineural invasion