Table 3. Results of multivariate Cox regression modeling of overall survival and recurrence-free survival in N1a colon cancer.
Characteristics | Overall survival | Disease-free rate | |||||
---|---|---|---|---|---|---|---|
Hazard ratio | 95% CI | P value | Hazard ratio | 95% CI | P value | ||
Age | < 75 | 1.00 | 0.442 | 1.00 | 0.997 | ||
≧ 75 | 0.98 | 0.96 ~ 1.02 | 0.99 | 0.97 ~ 1.02 | |||
Gender | male | 1.00 | 0.384 | 1.00 | 0.099 | ||
female | 0.92 | 0.89 ~ 1.12 | 0.95 | 0.62 ~1.54 | |||
Performance | 0~1 | 1.00 | 0.949 | 1.00 | 0.280 | ||
2 | 1.07 | 0.14 ~ 8.07 | 0.57 | 0.21 ~ 1.58 | |||
Location | right | 1.00 | 0.391 | 1.00 | 0.598 | ||
left | 0.63 | 0.33 ~ 1.22 | 0.171 | 0.78 | 0.49 ~ 1.26 | 0.313 | |
sigmoid | 0.78 | 0.43 ~ 1.43 | 0.418 | 0.86 | 0.55 ~ 1.35 | 0.515 | |
Differentiation | well | 1.00 | 0.349 | 1.00 | 0.719 | ||
moderate | 2.19 | 0.19 ~ 25.21 | 0.529 | 0.55 | 0.09 ~ 3.45 | 0.527 | |
poor | 0.75 | 0.10 ~ 5.57 | 0.777 | 0.62 | 0.19 ~ 2.01 | 0.428 | |
Tumor depth | T1+2 | 1.00 | 1.00 | 0.125 | |||
T3+4 | 1.129 | 0.51 ~ 2.52 | 0.767 | 1.48 | 0.89 ~ 2.44 | ||
Invasion | Present | 1.08 | 0.63 ~ 1.89 | 0.765 | 0.94 | 0.62 ~ 1.43 | 0.783 |
Absent | 1.00 | 1.00 | |||||
CEA level | ≦5 | 1.00 | 1.00 | ||||
> 5 | 3.42 | 2.05 ~ 5.73 | <0.001 | 3.28 | 2.24 ~ 4.81 | <0.001 | |
LN sampling number | ≧ 12 | 1.00 | 1.00 | ||||
< 12 | 2.11 | 1.28 ~ 3.41 | 0.007 | 1.48 | 0.98 ~ 2.16 | 0.056 | |
Treatment of chemotherapy | (+) | 1.21 | 0.61 ~ 2.42 | 0.591 | 0.69 | 0.37 ~ 1.31 | 0.262 |
(-) | 1.00 | 1.00 |