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. 2015 Sep 18;10(9):e0137053. doi: 10.1371/journal.pone.0137053

Table 3. Results of multivariate Cox regression modeling of overall survival and recurrence-free survival in N1a colon cancer.

Characteristics Overall survival Disease-free rate
Hazard ratio 95% CI P value Hazard ratio 95% CI P value
Age < 75 1.00 0.442 1.00 0.997
≧ 75 0.98 0.96 ~ 1.02 0.99 0.97 ~ 1.02
Gender male 1.00 0.384 1.00 0.099
female 0.92 0.89 ~ 1.12 0.95 0.62 ~1.54
Performance 0~1 1.00 0.949 1.00 0.280
2 1.07 0.14 ~ 8.07 0.57 0.21 ~ 1.58
Location right 1.00 0.391 1.00 0.598
left 0.63 0.33 ~ 1.22 0.171 0.78 0.49 ~ 1.26 0.313
sigmoid 0.78 0.43 ~ 1.43 0.418 0.86 0.55 ~ 1.35 0.515
Differentiation well 1.00 0.349 1.00 0.719
moderate 2.19 0.19 ~ 25.21 0.529 0.55 0.09 ~ 3.45 0.527
poor 0.75 0.10 ~ 5.57 0.777 0.62 0.19 ~ 2.01 0.428
Tumor depth T1+2 1.00 1.00 0.125
T3+4 1.129 0.51 ~ 2.52 0.767 1.48 0.89 ~ 2.44
Invasion Present 1.08 0.63 ~ 1.89 0.765 0.94 0.62 ~ 1.43 0.783
Absent 1.00 1.00
CEA level ≦5 1.00 1.00
> 5 3.42 2.05 ~ 5.73 <0.001 3.28 2.24 ~ 4.81 <0.001
LN sampling number ≧ 12 1.00 1.00
< 12 2.11 1.28 ~ 3.41 0.007 1.48 0.98 ~ 2.16 0.056
Treatment of chemotherapy (+) 1.21 0.61 ~ 2.42 0.591 0.69 0.37 ~ 1.31 0.262
(-) 1.00 1.00