Fig 1. Behavioral paradigm.

(A) Illustration of behavioral task [33], in which animals are required to reach through a narrow slit to grasp and retrieve a pellet into their cage. (B) Picture of animals grasping a pellet. Green line shows an example reach trajectory from which kinematic analyses are performed. (C) Overall behavioral/recording paradigm involved four blocks: a 2-h block of spontaneous recording (Sleep₁), a block of skilled motor training (Reach₁), another 2-h block of spontaneous recording (Sleep₂), followed by a final reach block (Reach₂).