Table 2. Parameters with the highest diagnostic prediction in tumor parenchyma (TP) and peritumoral area (PT) for distinction of a pair of brain tumors according to ROC analysis.
Comparison group | ROI Position | Most powerful parameter | AUC | Sensitivity | Specificity | Cut-off value |
---|---|---|---|---|---|---|
HGG & vs LGG $ | TP | Ve | 0.79 | 0.76 | 0.79 | 0.154 * |
PT | K trans | 0.64 | 0.52 | 0.80 | 0.031min -1 * | |
HGG & vs PCNSL $ | TP | Ve | 0.64 | 0.53 | 0.79 | 0.389 # |
PT | K trans | 0.68 | 0.78 | 0.60 | 0.0145min -1 * | |
HGG & vs Metastases $ | TP | iAUC | 0.80 | 0.84 | 0.69 | 10.363 # |
PT | ADC | 0.70 | 0.96 | 0.47 | 1357.4 # | |
Menigioma & vs LGG $ | TP | Ve | 0.97 | 0.98 | 0.89 | 0.264 * |
PT | ADC | 0.65 | 0.67 | 0.70 | 1178.8 # | |
PCNSL & vs LGG $ | TP | Kep | 0.87 | 0.76 | 0.77 | 0.818min -1 * |
PT | ADC | 0.65 | 0.63 | 0.69 | 1459.0×103mm 2 /s # | |
Metastases & vs LGG $ | TP | Ve | 0.93 | 0.82 | 1.00 | 0.196 * |
PT | ADC | 0.80 | 0.88 | 0.69 | 1471.6×103mm 2 /s # | |
PCNSL & vs. Metastases $ | TP | No | - | - | - | - |
PT | No | - | - | - | - |
LGG: Low grade gliomas; HGG: High grade gliomas; PCNSL: primary central nervous system lymphoma
&: The first tumor group.
$: Comparative tumor group.
*: If the parameter’s value is higher than the cut-off point, the tumor is more likely to be the tumor type in the first tumor group.
#: If the parameter’s value is higher than the cut-off point, the tumor is more likely to be the tumor type belongs to the comparative tumor group.