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. 2014 Nov 21;55(11):7499–7507. doi: 10.1167/iovs.14-14872

Figure 3.

Figure 3

BrdU-positive cells in the trabecular meshwork outflow pathways. (A, B) Relative number of BrdU-positive cells in the different regions of the TM outflow pathways in group 1 (A) and group 2 (B) eyes. Means ± SEM are shown. *P < 0.05. **P < 0.01. ***P < 0.001. (C) Immunohistochemical staining of Schlemm's canal endothelium in a group 2 eye for BrdU (green) and CD31 (red). Cell nuclei are stained with DAPI (blue). The arrows point toward a BrdU-/CD31-positive cell in Schlemm's canal endothelium. (D) Immunohistochemical staining of Schlemm's canal endothelium in a group 2 eye for BrdU (green) and OCT4 (red). Nuclei are stained with DAPI (blue). The arrows point toward a BrdU-positive cell in Schlemm's canal endothelium, arrowheads mark nonnuclear labeling in the JCT.